Effect of dextran on blood typing and crossmatching.

نویسندگان

  • P ROCHE
  • R A DODELIN
  • W L BLOOM
چکیده

By PAT ROCHE, JR., M.D., RICHARD A. DODELIN, M.D. AND WALTER L. BLOOM, M.D. D EXTRAX is omie of the newest of macromolecular substances sihich have heems showns capal)le of expaiudimsg plasma volumme.15 Imi the past-, omse disadvanut-age to the imitravensous imujectionu of substances of large molecular size has heens the clumping amid! rounleaux formations of erythrocytes6’ which makes subseqinenut typinig and crossmat-chimsg of blood difficult. Recemst stundies have shosvns that the larger molecular sizes of partially hydrolyzed dext-rans produce marked aggregations amsd es’ens instravascular aggregations of eryt-hrocytes.8 It svas shosimi thatthis ii’as related to the proportions of large molecular fractionss ins the particular preparations used, simice dextrams of a small molecular size did nsot produce this effect-. Dextrans used climsically itt Ssvedens amid ins Emugland carries a precautionsarv nsote thatblood for t-ypimsg and crossmatchinsg he remos-’ed prior to

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عنوان ژورنال:
  • Blood

دوره 7 3  شماره 

صفحات  -

تاریخ انتشار 1952